In summer of 1993, Professor Manalo forged an agreement with the Dean of the University of the Philippines College of Music, Prof. Juan Ramos to have the string players of PREDIS Chamber Orchestra musicians to rehearse and hold a joint summer program with the music students of UP College of Music. Other orchestra musicians from other schools also participated in this program. This group performed various concerts at the UP College of Music’s Nicanor Abelardo Hall, and had performances with foreign guest conductors Jeffrey Rink, Sebastian Bereau and Yaacov Bergman. From this base of accomplished musicians, the Manila Youth Symphony Orchestra (MYSO) was born, based at the St. Scholastica’s College of Music.

Under the leadership of Prof. Basilio Manalo, the MYSO launched into a Mindanao-Cebu concert tour where they had concerts in various venues in Davao, Bukidnon, Iligan City, Cagayan de Oro and Cebu City. In Cebu, they had a joint concert with the Cebu Youth Symphony Orchestra (CYSO) founded by the concert pianist Ingrid Sala Santamaria. With Professor Manalo and Sr. Mary Placid Abejo’s encouragement, PREDIS trained musicians and MYSO members Jeffrey Solares, Anthony Reyes and Val Cad stayed on in Cebu and helped develop and raise the level of excellence of the CYSO to become at par with the country’s best young musicians.

The MYSO also had concert series in the Cultural Center and in the St. Cecilia’s Hall. During the years 1997, 1998 and 1999, they had concert series performances at the Cultural Center of the Philippines performing the major works of Beethoven, Brahms, Berlioz, Shostakovich, Dvorak, Wagner and Mahler. Compositions by leading Filipino composers such as Antonino Buenaventura, Lucio San Pedro, Francisco Feliciano and Lucrecia Kasilag were also performed in these concerts. The featured soloists in these concerts included international artists such as pianist Felipe Ramirez and Filipino artists such as cellist Wilfredo Pasamba, violinists Arturo Molina and Gina Medina, pianist J. Greg Zuniega, and pop song diva Lani Misalucha.

During the year 2000, MYSO had special concerts with Prof. Christoph Poppen, conductor of the Munich Chamber Orchestra. They also had special workshop with the German concert cellist Klaus Kanngeiser.